Physicians' Academy for Cardiovascular Education

Imaging and Biomarkers to Assess Cardiovascular Risk

Slides (presentation) - July 8, 2010

Presentation topic Imaging and Biomarkers to Assess Cardiovascular Risk and Guide Treatment
VascularImagingTechnologies
The Importance of Vascular Imaging
What Makes a Good Surrogate Marker?
Quantitative Coronary Angiography (QCA)
Data Supporting QCA as a Surrogate
Glagov’s Remodelling Hypothesis
Pros and Cons of QCA
What is IMT ?
Carotid Anatomy
Carotid Intima Media Thickness (CIMT)
Evidence That CIMT Predicts Clinical Disease
Association Between CIMT and Risk of Stroke and MI
Cardiovascular Health Study: Baseline CIMT Predictive of CHD
IMT and Progression of Atherosclerosis
TheARBITER-2StudyShowedaTreatmentEffectonProgressionofAtherosclerosisMeasuredbyCIMT
Indirect Evidence for IMT / IVUS Predicting Clinical Events
CIMT Correlative Analysis – Results
Pros and Cons of CIMT
Plaque Progression Measured by IVUS Correlates With Cardiovascular Risk
Beneficial Effect of Interventions on Mean Change in Total Atheroma Volume Demonstrated by IVUS
IntensiveStatinTherapyreducesall-CauseDeathorMajorCVEvents
Pros and Cons of IVUS
24 Months of Statin Treatment Induces Regression of Atherosclerosis Determined by CMR
Pros and Cons of CMR
Summary

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