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The concept of Diabetes & CV risk:A lifetime risk challenge
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The Cardiovascular Continuum
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RAS Blockade Across the CV Continuum
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2007 ESH/ESC Guidelines: Choice ofAntihypertensive Drugs
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VALUE : Odds Ratios Over Time
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VALUE: Endpoints while on Monotherapy
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LIFE: Primary Composite Endpoint
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Risk Reduction: ARB versus Control
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MOrbidity and Mortality after Stroke – Eprosartan vs. Nitrendipine in Secondary Prevention
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SCOPE: First Major Cardiovascular Events
in Patients with a Previous Stroke
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Antagonism of Angiotensin II-Induced Effects by Candesartan and Losartan
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Insurmountable and Surmountable
Antagonism: Relation to Duration of Binding
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A Placebo Controlled ABPM Comparison of Candesartan 8 mg and Losartan 50 mg
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Candesartan Cilexetil vs Losartan : Mean Change From Baseline to Week 8 in Systolic ABP
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Comparison of the Efficacy of Candesartan & Losartan: Meta-Analysis of Trials in the Treatment of Hypertension
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Candesartan & Losartan-Antihypertensive Effects: Systolic BP in Direct Comparator Trials
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Candesartan & Losartan-Antihypertensive Effects: Systolic BP in Direct Comparator Trials
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Candesartan & Losartan-Antihypertensive Effects: Diastolic BP in Direct Comparator Trials
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Potential Benefits of Additional BP Reductions
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Hypothesis and Aim
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Selection Method
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The “Real-Life” Study: Candesartan v Losartan
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Blood Pressure Reduction
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Concomitant Medication
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Primary Outcome: Candesartan v Losartan
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Risk of Separate Endpoints
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Candesartan v Losartan: Mortality in Heart Failure Patients
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Candesartan v Losartan: Mortality in Heart Failure Patients
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Candesartan v Losartan: Mortality in Heart Failure Patients
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