Physicians' Academy for Cardiovascular Education

The case for intensive lipid management: The opportunities and issues for cardiologists

Slides (presentation) - June 16, 2011

The case for intensive lipid management:
The opportunities and issues for cardiologists


Prof. D John Betteridge,

Emeritus Professor of Endocrinology and Metabolism UCL
Associate Dean Royal Society of Medicine, Consultant Physician, University College London Hospitals


Click on slides below to view presentation



BMJ 1975, 4 500-502
The Fate of LDL
FH3: mutations in PCSK9 Proprotein
Familial Hypercholesterolaemia
LDL-C Distribution and CAD Incidence
LDL and Atherogenesis
Macrophages and Foam Cells
From Association to Cause
Problems with Early Trials
Effects of Statins
Statins:The Evidence Base.
CHD Risk Despite Statin Therapy
Early Primary and Secondary CVD Prevention Trials
PROVE-IT Trial
Intensive Lipid Lowering with Atorvastatin
Treat to New Targets: Lipid Effects
Primary Efficacy Outcome Measure: First Major
Statin Therapy in Secondary Prevention
Meta-Analysis Cardiovascular Outcomes I
Implications of Recent Trials Adult Treatment Panel III Guidelines
Statins and Stroke Reduction
Heart Protection Study Stroke Outcomes
SPARCL
High-Dose Atorvastatin after Stroke or Transient Ischaemic Attack

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