Physicians' Academy for Cardiovascular Education

HDL Master Class

held on September 29-30, 2011 in Prague, Czech Republic

Sep. 30, 2011

Modifying the functionality of HDL in future lipid management

The Master Class was a dynamic meeting with state of the art lectures, clinical debates, and practical workshops.
The meeting aimed to educate participants with state-of-the-art information about HDL cholesterol, and its role in current and future prevention of cardiovascular disease.

During this interactive programme an in-depth review was provided on the epidemiology, the metabolism and mechanisms of the protection that HDL cholesterol confers. Further, therapeutic strategies targeted to modify HDL cholesterol were discussed. The scientific programme was designed to set the stage for a new area of cardiovascular protection.

The educational objectives of this Master Class were:
  • To explore the role of HDL-C in atherosclerosis
  • To understand the importance of HDL functionality
  • To review the role of CETP inhibition in atherogenesis
  • To evaluate the effects of new HDL-C modifying therapies on the risk of cardiovascular events in CV risk patients
  • To understand the importance of HDL-C modification in patients at high CV risk, such as DM and metabolic syndrome
  • To understand the pharmacologic rationale and clinical impact of new clinical trial data on HDL-C modification for patients with atherosclerosis
  • To develop a consensus on practical guidelines for day-to-day lipid management of patients with atherosclerosis and CV risk

View the presentations held during the Master Class

The epidemiology of HDL-C and CV disease: Does HDL protect against atherosclerotic events?

Dr. Kees Hovingh
Academic Medical Centre
Amsterdam, The Netherlands

HDL mediated efflux of cholesterol from the arterial wall

Prof. John Chapman
INSERM, Hôpital de la Pitié
Paris, France

HDL C concentration versus HDL particle function

Prof. Ulf Landmesser
University Hospital Zürich
Zürich, Switzerland

The role of the CETP protein in reverse cholesterol transport and atherogenesis

Prof. Chris Packard
Western Infirmary
Glasgow, United Kingdom

Endothelial function and blood pressure

Prof. John Deanfield
University College London
United Kingdom

Structural and functional imaging

Prof. Robin Choudhury
John Radcliffe Hospital
Oxford, United Kingdom

Diabetic dyslipidemia: the pro-atherogenic role of CETP

Prof. John Betteridge
University College London
United Kingdom

Emerging targets in HDL modification

Prof. John Kastelein
Academic Medical Centre
Amsterdam, The Netherlands

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