Physicians' Academy for Cardiovascular Education

Latest insights from clinical trials

Slides (presentation) - Oct. 5, 2012

Latest insights from clinical trials:The unassailable case for LDL-c lowering

Selection of slides prepared & presented by:

Prof. Kausik Ray, MD
Professor of cardiovascular disease prevention, Honorary consultant cardiologist St George’s Hospital NHS Trust

at PACE Lipid Master Class
Budapest, September 21-2, 2012

View presentation, click on images

The overwhelming case for LDL-C lowering
4S Primary Endpoint: Total Mortality
HPS: Effects of Simvastatin
ASCOT-LLA
CARDS
CTT Collaboration
Cholesterol Trialist Collaboration
Only high dose statins
All-Cause Death or Major CV Events in
Is there benefit from an LDL of
Cholesterol Trialist Collaboration
Meta-Analysis of Intensive Statin Therapy
Meta-Analysis of Intensive Statin Therapy
PROVE IT-TIMI 22
TNT: Incidence of First Major
JUPITER
JUPITER
JUPITER
Event rates by achieved LDL-C in trials
PROVE IT Safety Result
Adverse Event Profiles TNT
CTT Lancet 2012
Statins increase risk of Dysglycaemia
Statins and DYSGLYCAEMIA vs CVD Risk
New-Onset T2DM
Evidence for Clinical Benefit
Summary

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