Physicians' Academy for Cardiovascular Education

PPAR gamma activation Impact on pathways of clinical care

Slides (presentation) - Dec. 24, 2012

Slide lecture program (21 slides): View & Download

  1. New paradigm of multiple risk factormanagement
  2. TRIPOD: Treating insulin resistance reduces incidence of type 2 diabetes
  3. TRIPOD & PIPOD: Evidence that insulin resistance causes B-cell failure
  4. Anticipated results from large multicenter trials in (pre)diabetes
  5. DREAM Background and study objective
  6. DREAM Study design
  7. DREAM: Rosiglitazone prolongs time to occurrence of new-onset diabetes or death
  8. DREAM results: Summary
  9. TZDs blunt diabetes progression
  10. Anticipated results from large multicenter trials in (pre)diabetes
  11. CHICAGO: Background and rationale
  12. CHICAGO: Study design
  13. CHICAGO: Baseline risk factors
  14. CHICAGO: Treatment effect on glucose control
  15. CHICAGO: Treatment effect on posterior wall mean CIMT
  16. CHICAGO: Treatment effect on posterior wall mean CIMT in prespecified subgroups
  17. CHICAGO: Summary
  18. CHICAGO: Implications
  19. Aggressive medical therapy in diabetes
  20. Summary: Optimizing outcomes in patients with multiple CVD risks
PPAR gamma activation Impact on pathways of clinical care
New paradigm of multiple risk factormanagement
TRIPOD:
TRIPOD & PIPOD:
Anticipated results from large multicenter trials in (pre)diabetes
DREAM Background and study objective
DREAM Study design
DREAM:
DREAM results: Summary
TZDs blunt diabetes progression
Anticipated results from large multicenter trials in (pre)diabetes
CHICAGO: Background and rationale
CHICAGO: Study design
CHICAGO: Baseline risk factors
CHICAGO: Treatment effect on glucose control
CHICAGO: Treatment effect on posterior wall mean CIMT
CHICAGO: Treatment effect on posterior wall mean CIMT
CHICAGO: Summary
CHICAGO: Implications
CHICAGO: Implications
Aggressive medical therapy in diabetes
Summary: Optimizing outcomes in patients with multiple CVD risks

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