Statin-loaded HDL nanoparticles
Raphaël Duivenvoorden, MD, internist, AMC Amsterdam
Recorded: Tergooiziekenhuizen, Hilversum, The Netherlands, January 9, 2014
Literature • 23-1-2014 • Duivenvoorden et al., Nat Commun. 2014
Statin-loaded HDL nanoparticles have local anti-inflammatory effects on plaques
HDL nanoparticles can deliver statin to atherosclerotic plaques in mice, and reduce inflammation and total plaque area.
Statin-loaded HDL nanoparticle
In Nature Communications January 2014 Raphaël Duivenvoorden describes an innovative nanotechnique to reduce the risk of a recurrent myocard infarct, in which inflammation is a key factor. A statin-loaded HDL-nanoparticle which by nature attaches itself to a plaque, appeares to be able to reduce inflammation in an animal model.The information and data provided in this program were updated and correct at the time of the program development, but may be subject to change.
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