Physicians' Academy for Cardiovascular Education

Statin-loaded HDL nanoparticles

Jan. 23, 2014 - Raphaël Duivenvoorden - Raphaël Duivenvoorden

 

 

Raphaël Duivenvoorden, MD, internist, AMC Amsterdam
Recorded: Tergooiziekenhuizen, Hilversum, The Netherlands, January 9, 2014
 

In Nature Communications January 2014 Raphaël Duivenvoorden describes an innovative nanotechnique to reduce the risk of a recurrent myocard infarct, in which inflammation is a key factor. A statin-loaded HDL-nanoparticle which by nature attaches itself to a plaque, appeares to be able to reduce inflammation in an animal model.

 Literature • 23-1-2014 • Duivenvoorden et al., Nat Commun. 2014

Statin-loaded HDL nanoparticles have local anti-inflammatory effects on plaques

HDL nanoparticles can deliver statin to atherosclerotic plaques in mice, and reduce inflammation and total plaque area.

E-Learning • Raphaël Duivenvoorden

Statin-loaded HDL nanoparticle

In Nature Communications  January 2014 Raphaël Duivenvoorden describes an innovative nanotechnique to reduce the risk of a recurrent myocard infarct, in which inflammation is a key factor. A statin-loaded HDL-nanoparticle which by nature attaches itself to a plaque, appeares to be able to reduce inflammation in an animal model.