2014: the major lipid developments in review
Prof. John Kastelein, Amsterdam, (PACE director) reviews the major news from 2014 on the 3 lipoproteins: LDL-c, HDL-c and TG that provide new understanding and implications for the fight against atherosclerosis.
Key take home messages:
- TG rich lipoprotein causal in pathway for atherogenesis, and target for therapy
- End of HDL-c hypothesis and start of Cholesterol Efflux capacity (confirmed by HDL-c)
- Prove of LDL-c lowering hypothesis with non statin therapy by IMPROVE-IT
John J.P. Kastelein, MD PhD FESC
ISA 2015 Chairman
Professor of Medicine, Dept. of Vascular Medicine, Academic Medical Center / University of Amsterdam
Amsterdam, The Netherlands
The information and data provided in this program were updated and correct at the time of the program development, but may be subject to change.