Physicians' Academy for Cardiovascular Education

Optimizing RAAS inhibition in Heart failure: Novel treatment considerations for the management of hyperkalemia

Florence, Italy - 23 May 2016

July 4, 2016

EBAC Accredited symposium held during Heart Failure 2016, Florence, Italy

View videorecording of lectures

ESC Heart Failure Congress, Florence, Italy - May 23.

The educational objectives of this symposium were:

  • To understand the need for optimisation and maintenance of RAASi therapy in HFrEF;
  • To understand the reasons why target doses are not reached for RAASi;
  • To describe new pharmacological options for inhibiting RAAS and for management of hyperkalemia in patients with HFrEF treated with RAASi
  • To describe the limitations and challenges to RAASi use in HF, in order to identify new treatment options for achieving better outcomes in HF patients.


RAAS inhibition in heart failure: Corner stone of therapy & potassium homeostasis

Many HF patients are treated suboptimally, with hyperkalemia being one of the underlying reasons. Prof Faiez Zannad, Nancy, France, considers this clinical scenario, its consequences and how it can be managed.


Hyperkalemia: Novel treatment strategies to manage potassium levels in heart failure

Conventional therapies to treat hyperkalemia are associated with clinical complications. Dr. Peter van der Meer, Groningen, The Netherlands, discusses the mechanism and efficacy and safety results of two new therapeutic options that lower potassium levels: patiromer and ZS-9.


The future of HF management: How does potassium binding fit within pharmacological treatment of heart failure?

 Prof. Kenneth Dickstein considers the increase in potassium levels that arise as a consequence of blocking the renin-angiotensin system. Hyperkalemia is often a reason for not following guideline-recommended therapy, which underlines the need for novel potassium-lowering therapy.


This symposium was supported by an unrestricted educational grant from AstraZeneca.

In compliance with EBAC/ EACCME guidelines, all speakers/Chairpersons participating in this programme have disclosed or indicated potential conflicts of interest which might cause a bias in the presentations.

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3 minute education • 21-5-2016, ESC HF 2016, Florence, Italy, Adriaan Voors (Groningen, The Netherlands)

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