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• Multiple metabolic abnormalities contribute to hyperglycaemia in T2DM 1:07
• Recommended treatment algorithms and factors based on which to individualise management 4:42
• Different antidiabetic drugs target different pathogenic mechanisms, with complementary effects 8:12
• What is known about the efficacy of the many possible combinations of antidiabetic drugs? 25:22
• Trials addressing safety concerns associated with novel diabetes agents 28:39
• Some antihyperglycaemic agents show a benefit on CV outcomes 35:22
• Considerations for selecting therapies 42:25