Physicians' Academy for Cardiovascular Education

ACEi/ARB therapy at discharge associated with lower mortality and readmission rates in HFrEF

Initiation, Continuation, or Withdrawal of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers and Outcomes in Patients Hospitalized With Heart Failure With Reduced Ejection Fraction

Literature - Gilstrap LG, Fonarow GC, Desai AS, et al. - J Am Heart Assoc. 2017;6:e004675

Main results


In a large cohort of 16 052 HFrEF patients, the continuation or initiation of ACEi/ARB therapy at the time of discharge after admission for ADHF was associated with lower mortality and readmission rates, compared with those who discontinued or did not start therapy. These findings provide further evidence related to guideline recommendations for these patients.


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