Physicians' Academy for Cardiovascular Education

Lower achieved SBP and DBP associated with more CV events

Achieved blood pressure and cardiovascular outcomes in high-risk patients: results from ONTARGET and TRANSCEND trials

Literature - Böhm M, Schumacher H, Teo KK, et al. - Lancet. 2017; published online ahead of print

Main results


In high-risk CV patients, lowering SBP to less than 130 mmHg or DBP to less than 75 mmHg, is associated with increased rates for CV death, MI and HF, but not stroke. These findings suggest that in some patients at low SBP on treatment, blood pressure medication might have to be reduced to avoid adverse outcomes, since treat to target does not mean treat under target.


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Find this article online at The Lancet

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