Physicians' Academy for Cardiovascular Education

Brain amyloid in later life increases with number of midlife vascular risk factors

Association Between Midlife Vascular Risk Factors and Estimated Brain Amyloid Deposition

Literature - Gottesman RF, Schneider ALC, Zhou Y, et al. - JAMA 2017;317(14):1443-1450

Main results

Conclusion

An increased number of midlife, but not late life vascular risk factors was associated with elevated brain amyloid in later life. The relationships between vascular risk factors and brain amyloid did not differ by race, nor by status of the APOE allele.

References

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