Physicians' Academy for Cardiovascular Education

Long-term gluten consumption not associated with CHD risk in healthy individuals

Long term gluten consumption in adults without celiac disease and risk of coronary heart disease: prospective cohort study

Literature - Lebwohl B, Cao Y, Zong G, et al. - BMJ 2017; 357: j1892

Main results


In a large, prospective study, the consumption of foods containing gluten was not significantly associated with the risk of CHD. Estimated gluten intake was correlated with whole grain and refined grain intake. The adjusted analyses on refined and whole grain intake suggest the potential that people who severely restrict gluten intake may also significantly limit their intake of whole grains. This may be associated with adverse CV outcomes. These findings do not support a gluten restricted diet in the general population of asymptomatic individuals without celiac disease for the reduction of CHD risk.


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