Physicians' Academy for Cardiovascular Education

BNP and troponin I measurements did not improve risk stratification of acute HF patients

Measurement of troponin and natriuretic peptides shortly after admission in patients with heart failure—does it add useful prognostic information? An analysis of the Value of Endothelin Receptor Inhibition with Tezosentan in Acute heart failure Studies (VERITAS)

Literature - Cleland JGF, Teerlink JR, Davison BA, et al, for the VERITAS Investigators - Eur J Heart Failure 2017; 19(6):739–747

Main results

Conclusion

For AHF patients in the VERITAS studies, the predictive value of conventional clinical assessments made shortly after admission was poor at identifying death or readmission at 30 days, but somewhat better at predicting all-cause mortality at 90 days. Measurement of BNP and troponin I at admission did not substantially improve the prediction of any of the specified outcomes.

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