Physicians' Academy for Cardiovascular Education

Air pollution and traffic noise associated with increase in CVD risk factors

Long-term exposure to road traffic noise, ambient air pollution, and cardiovascular risk factors in the HUNT and lifelines cohorts

Literature - Cai Y, Hansell AL, Blangiardo M, et al. - Eur Heart J 2017; published online ahead of print

Main results


In two large European cohorts, long-term exposures to road traffic noise and ambient air pollution were significantly associated with increased systemic inflammation (hsCRP), blood glucose levels and risk for potential elevation of lipid levels. These data suggest a possible link between noise or air pollution with CVD and highlight the importance to consider environmental causes in the prevention of CVD as well as the need of collective efforts to mitigate noise and air pollution.

Editorial comment

In their editorial article [6], Münzel et al highlight the global health burden of environmental stressors and comment on the study published by Cai et al as follows: ‘As commented by the authors, the observed effects of road traffic noise and air pollution on CVD risk factors were small. However, given the high proportion of the population exposed to high levels of these pollutants, the effect of this observation could be that the entire distribution of these risk factors may be shifted towards a less favourable profile at population level, i.e. ‘at-risk’ populations may be increased.’

They also discuss open questions resulting from studies examining the associations between air pollution and traffic noise, like for example the finding that the link between road traffic noise and CVD disappeared after adjustment for air pollution, and the other way around, and they conclude:

‘For the future, the development of technologies that provide measures of personal environmental exposure in conjunction with measures of health may provide an unprecedented opportunity for research and may allow an extraordinary understanding of the interactions between environment and health. To conclude, with this new study by Cai et al., the evidence that environmental stressors can cause cardiovascular and metabolic disease is growing, although mechanistic insights into how traffic noise and air pollution interplay are still warranted.’


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Find this article online at Eur Heart J

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