Physicians' Academy for Cardiovascular Education

Aspirin discontinuation in CVD prevention is associated with increased CV risk

Low-Dose Aspirin Discontinuation and Risk of Cardiovascular Events: A Swedish Nationwide, Population-Based Cohort Study

Literature - Sundström J, Hedberg J, Thuresson M, et al. - Circulation. 2017;136:1183-1192

Main results

Conclusion

The discontinuation of low-dose long-term aspirin use for CVD prevention in the absence of major surgery or bleeding, was associated with a >30% increased CV risk, shortly after discontinuation. These findings support the use of aspirin in CVD prevention, and justifies further measures to ensure treatment persistence in this setting.

References

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