Physicians' Academy for Cardiovascular Education

Fewer ventricular arrhythmias with angiotensin-neprilysin vs angiotensin inhibition in HF

Effects of angiotensin-neprilysin inhibition as compared to angiotensin inhibition on ventricular arrhythmias in reduced ejection fraction patients under continuous remote monitoring of implantable defibrillator devices.

Literature - de Diego C, González-Torres L, Núñez JM, et al. - Heart Rhythm 2017; published online ahead of print

Main results

Conclusion

In HFrEF patients with an ICD under remote control, angiotensin-neprilysin inhibition as compared to angiotensin inhibition alone decreased ventricular arrhythmias, leading to a reduction of appropriate ICD shocks.

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