Physicians' Academy for Cardiovascular Education

Practical guidance on implementation of ESC recommendations on management of iron deficiency in chronic HF

News - Oct. 16, 2018

Patients with chronic heart failure (CHF) often suffer from iron deficiency, which is associated with decreased exercise performance, impaired health-related quality of life and a worse prognosis, irrespective of the presence of anemia. In 2016, the European Society of Cardiology (ESC) published guidelines on the management of HF, which also formulated recommendations on the management of iron deficiency, a common and important co-morbidity. Iron deficiency is, however, still under-diagnosed and under-treated in clinical practice, possibly due to a lack of practical, easy-to-follow advice on how to diagnose and treat iron deficiency. Therefore, a working group now set out to compose practical guidance, relating to the procedures for screening, diagnosis and treatment of iron deficiency in patients with CHF.

2016 ESC Guidelines on management of iron deficiency in HF

Practical recommendations of the working group

Other considerations

Several knowledge gaps relating to the role of IV iron therapy in HF patients remain. As a consequence, some of the practical recommendations are based on expert opinion of the working group instead. Ongoing trials will further address the effects of IV iron therapy in HF patients, including the impact of IV iron therapy on morbidity and mortality in systolic CHF patients with iron deficiency (FAIR-HF2 and IRONMAN studies) and the efficacy and safety of IV iron in patients with HFpEF or acute HF and iron deficiency (FAIR-HFpEF and AFFIRM-AHF studies).

Find this article online at Eur J Heart Fail.

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