Physicians' Academy for Cardiovascular Education

What to do if potassium levels increase in HF?

10' education - Aug. 7, 2023 - Mikhail Kosiborod, MD - Kansas City, MO, USA

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  • Patient case 00:26
  • What are the therapeutic options? 03:14
  • Novel potassium binders 06:07
  • The REALIZE-K-trial: evaluating whether SZC can enable RAASi optimization in HFrEF patients with hyperkalemia 10:40
  • Summary 12:00

Which management option for the treatment of hyperkalemia in patients with HFrEF has the least limitations?

  • A. Low potassium diet
  • B. Discontinuation or dose reduction of RAASi-based therapy
  • C. Traditional potassium binders (sodium polystyrene sulphonate)
  • D. Novel selective potassium binders (sodium zirconium cyclosilicate (SZC) or patiromer)
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Educational information

This lecture by Mikhail Kosiborod, MD was part of the EBAC-accredited symposium "Breaking barriers in guideline-based RAASi therapy: Solving issues with hyperkalemia" at ESC Heart Failure in Prague, Czech Republic.


Mikhail Kosiborod, MD is a Cardiologist and Vice President of Research at Saint Luke’s Health System, Executive Director of the Cardiometabolic Center Alliance, Director of Cardiometabolic Research and Co-Director of the Haverty Cardiometabolic Center of Excellence at Saint Luke’s Mid America Heart Institute, and Professor of Medicine at the University of Missouri-Kansas City.


This recording was independently developed under auspices of PACE-cme. The views expressed in this recording are those of the individual presenter and do not necessarily reflect the views of PACE-cme.


Funding for this educational program was provided by an unrestricted educational grant received from AstraZeneca.

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