Physicians' Academy for Cardiovascular Education

Stroke

Head-to-head comparison of risk scores for ischemic stroke in patients with AF and CKD

5' education - June 14, 2001 - Ype de Jong, MD

Novel findings with dual SGLT1 and SGLT2 inhibitor in diabetes patients

5' education - Nov. 23, 2020 - Prof. Deepak Bhatt, MD

Updates in the 2020 AF guidelines

3' education - Sep. 2, 2020 - Prof. Isabelle van Gelder, MD

Early rhythm control in AF patients improves outcomes

3' education - Aug. 29, 2020 - Prof. Paulus Kirchhof, MD

Challenges in prescribing DOACs for stroke prevention in AF

5' education - Mar. 2, 2020 - Prof. Freek Verheugt and John Eikelboom

Long-term treatment with dual antiplatelet therapy in patients with diabetes and stable CAD

3' education - Sep. 9, 2019 - Prof. Ph. Gabriel Steg

Long term benefits of antihypertensive and cholesterol-lowering treatment in hypertension

10' education - Nov. 20, 2018 - Dr. Ajay Gupta - London, UK

Higher healthy diet score is associated with a lower risk of mortality and CV events across the globe

3' education - Aug. 28, 2018 - Dr. Andrew Mente, Hamilton, ONT, Canada

Machine learning program predicts that drinking more coffee lowers risk of CVD and stroke

3' education - Nov. 13, 2017 - AHA 2017 - Anaheim, CA - Laura M Stevens - Aurora, CO, USA
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Stroke reduction with PPAR-Y antagonist pioglitazone

3' education - May 6, 2016 - Dubai, UAE - Dr Robert J Chilton
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PEGASUS: Clinical judgement needed

3' education - Mar. 16, 2015 - ACC 2015, San Diego - Valentin Fuster, MD Mount Sinai Hospital, New York,NY
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Translating new clinical trial data of DOACs for stroke prevention into clinical practice

3' education - Mar. 30, 2014 - VBWG at ACC - Michael Ezekowitz MD, PhD
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Neurological complications in diabetes

3' education - Apr. 23, 2014 - CDMC Almaty - Boris Mankovsky

AF more often detected by implantable vs. external loop recorder after stroke

Literature - June 22, 2021 - Buck BH et al. - JAMA. 2021

A randomized clinical trial compared the rate of detection of AF with use of an implantable loop recorder for 12 months vs. use of an external loop recorder for 30 days in patients with recent ischemic stroke without known AF.

Head-to-head comparison of risk scores for ischemic stroke in patients with AF and CKD

5' education - June 14, 2001 - Ype de Jong, MD
The predictive performance of six risk scores for ischemic stroke in patients with AF and CKD were validated. The Modified CHADS2 score showed good performance for discrimination and calibration in all kidney function categories.

The predictive performance of six risk scores for ischemic stroke in patients with AF and CKD were validated. The Modified CHADS2 score showed good performance for discrimination and calibration in all kidney function categories.

Comparable effectiveness of low-dose and regular-strength aspirin in patients with ASCVD

News - May 16, 2021

ACC 2021 The ADAPTABLE trial demonstrated similar effectiveness with 81 mg vs. 325 mg of daily aspirin in patients with established ASCVD. Also, major bleeding events were comparable between patients taking low-dose or regular-strength aspirin.

Aspirin alone lowers net clinical outcome compared to DAPT after TAVI

Literature - May 3, 2021 - Brouwer J, et al. - J Am Heart Assoc. 2021

This meta-analysis showed that patients without an indication for oral anticoagulation experienced fewer combined thromboembolic and bleeding events, and no increase in thromboembolic events after TAVI when treated with aspirin compared to those receiving DAPT.

Atypical PF4-dependent thrombosis and thrombocytopenia in some after COVID-19 vaccination

Literature - Apr. 22, 2021 - Scully M, et al. - N Engl J Med. 2021

This study described the clinical features of 23 patients who after receiving the first dose of ChAdOx1 nCoV-19 vaccine developed atypical platelet factor 4 (PF4)-dependent thrombosis and/or thrombocytopenia that resembles heparin-induced thrombocytopenia.

Modified CHADS2 shows best predictive performance for stroke across spectrum of kidney function

Literature - Apr. 13, 2021 - De Jong Y et al. - Eur Heart J. 2021

This study validated six risk scores for ischemic stroke in patients with AF across the spectrum of kidney function. The Modified CHADS2 score showed most consistent predictive performance in all kidney function categories.

Lower dose DOAC reduces net clinical outcome in patients with AF

Literature - Mar. 29, 2021 - Steffel J et al. - J Am Coll Cardiol. 2021

Lower dose edoxaban regimen decreased the net clinical outcome of major bleeding, stroke/systemic embolism, and death compared to higher dose edoxaban regimen in patients with AF.

Elevated Lp(a) associated with large artery atherosclerosis stroke and risk of recurrent stroke

Literature - Mar. 23, 2021 - Arnold M et al. - Eur Heart J. 2021

The prospective BIOSIGNAL cohort study showed that elevated Lp(a) was independently associated with LAA stroke etiology and risk of recurrent AIS or TIA in patients <60 years.

Hemorrhagic stroke related to increased mortality and disability in patients with AF

News - Mar. 23, 2021

ICS 2021 The Neuro-AFib study analyzed the frequency and outcomes of hemorrhagic strokes (HS) and ischemic strokes (IS) in patients with AF and showed that HS were related to increased mortality and disability as compared to IS in AF.

Risk of ischemic stroke in patients hospitalized with COVID-19 in the USA

News - Mar. 19, 2021

ISC 2021 Using data of the AHA COVID-19 CVD Registry, risk of ischemic stroke was 0.75% in patients hospitalized with COVID-19, which is lower than previously reported.

Silent MI associated with incident ischemic stroke

News - Mar. 19, 2021

ISC 2021 This analysis of the Cardiovascular Health Study showed that silent MI, defined as ECG evidence of MI without clinical recognition of an event, was significantly associated with incident stroke.

Icosapent ethyl reduces first and total stroke in patients with or high risk of CVD

News - Mar. 17, 2021

ISC 2021 Prespecified and post hoc analyses from REDUCE-IT showed that icosapent ethyl reduced first and total stroke, and first and total ischemic stroke compared to placebo in CVD patients or patients with diabetes and one CV risk factor.