Physicians' Academy for Cardiovascular Education

Stroke

No increased risk of stroke in AF patients without CV comorbidities

Literature - June 18, 2020 - Singleton MJ et al., - J Am Heart Assoc. 2020

This analysis of the REGARDS study showed that AF patients without CV comorbidities had no increased risk of stroke compared to individuals without AF or CV comorbidities.

Health professionals report decrease in STEMI admissions since COVID-19 outbreak

Literature - June 15, 2020 - Pessoa-Amorim G et al., - Eur Heart J Qual Care Clin Outcomes. 2020.

A survey conducted by the ESC among cardiologists and CV nurses revealed that 78.8% of responders perceived a decrease in STEMI admissions since the beginning of the COVID-19 outbreak.

P2Y12i monotherapy reduces risk of myocardial infarction compared to aspirin monotherapy

Literature - June 9, 2020 - Chiarito M et al., - The Lancet. 2020.

P2Y12i monotherapy reduces risk of MI, but not of stroke, all cause death, vascular death and bleeding, compared to aspirin monotherapy, in patients with established atherosclerosis.

Drinking filtered coffee associated with lower mortality

Literature - May 18, 2020 - Tverdal A et al., - Eur J Prev Cardiol. 2020.

A large Norwegian cohort study showed that drinking filtered coffee was associated with lower mortality than no coffee, while no association between coffee drinking and mortality was observed for those drinking unfiltered coffee.

AF associated with increased CV and total mortality in East Asian HFpEF patients

Literature - May 6, 2020 - Son MK, et al. - Heart. 2020

In a study of acute HF patients in a Korean registry, AF was more prevalent with increasing EF, and associated with increased CV and total mortality in HFpEF patients and increased risk of stroke in HFrEF and HFpEF patients.

Statin reduces total vascular events after stroke or TIA

Literature - May 6, 2020 - Szarek M, et al. - J Am Coll Cardiol. 2020

Total (first and subsequent) vascular events among patients with recent stroke or transient ischemic attack were reduced, as shown in a post-hoc analysis of the SPARCL trial.

Higher olive oil consumption associated with lower CV and CHD risk in U.S. adults

Literature - Mar. 24, 2020 - Guasch-Ferré M et al., - J Am Coll Cardiol. 2020.

In an analysis of two large U.S. cohorts, higher olive oil intake was associated with lower risk of major CVD and CHD risk compared to those consuming olive oil <1 per month.

Challenges in prescribing DOACs for stroke prevention in AF

5' education - Mar. 2, 2020 - Prof. Freek Verheugt and John Eikelboom
Although DOACs are safe and effective in AF patients, there are remaining challenges in prescribing DOACs. Freek Verheugt and John Eikelboom discuss 3 topics: underdosing, underuse and antidotes.

Although DOACs are safe and effective in AF patients, there are remaining challenges in prescribing DOACs. Freek Verheugt and John Eikelboom discuss 3 topics: underdosing, underuse and antidotes. With poll

P2Y12 inhibitor plus aspirin reduces risk of primary endpoint after acute ischemic stroke or TIA

News - Jan. 28, 2020

The phase III THALES trial with ticagrelor plus aspirin met the primary endpoint of stroke and death 30 days after acute ischemic stroke or TIA, but increased risk for bleeding, compared to aspirin alone.

Prestroke smoking status affects functional outcomes after acute ischemic stroke

Literature - Jan. 28, 2020 - Matsuo R et al., - Stroke. 2020

This registry study showed that smoking before stroke onset increases the risk of poor functional outcome and functional dependence 3 months after acute ischemic stroke.

LDL-c target of <70 vs. 100 mg/mL after stroke lowers risk of CV events

News - Nov. 25, 2019

AHA 2019 The Treat Stroke to Target (TST) trial randomized patients with ischemic stroke or TIA with evidence of atherosclerosis to one of two LDL-c targets and found a benefit of the lower target.

Optimism associated with reduced risk of CV events and all-cause mortality

Literature - Oct. 10, 2019 - Rozanski A, et al. - JAMA Network Open

A meta-analysis of 15 studies with more than 220,000 individuals showed that a mindset of optimism was associated with reduced risk of CV events and all-cause mortality.