CV health scores have decreased over the past 20 years, resulting in an increased risk of developing subclinical disease and incident CVD, as well as all-cause mortality.

Pre-meal yogurt consumption improved acute postprandial dysfunction after a high-fat, high-calorie meal in obese and non-obese women.

Rivaroxaban therapy is not beneficial for the prevention of stroke recurrence and associated with a higher risk of bleeding compared to aspirin in patients with embolic stroke of undetermined source.

In type 2 diabetic patients with a history of CABG, empagliflozin reduced significantly CV- and all-cause mortality, HF hospitalization, and incident or worsening nephropathy compared with placebo.

The CIRT trial evaluating low-dose methotrexate to lower CV risk has been stopped early, not based on any substantive safety concerns.

VBWG at ACC 2018 After lack of sham-controlled trials, the SPYRAL program has started to test the efficacy of renal denervation in patients with uncontrolled hypertension. Two pilot studies with a sham controlled group in patients without and with medications are nearly finished.

Healthy food intake was associated with having no coronary artery calcium, and in combination with higher cardiorespiratory fitness, it was also associated with lower CAC levels.

The European Commission (EC) has approved the use of evolocumab in patients with established atherosclerotic CVD (MI, stroke, PAD) to reduce CV risk.

A Google-driven nocebo effect may underlie statin intolerance, as countries with many websites on statin side-effects showed a higher prevalence of statin intolerance.

Patients with T2DM and atherosclerotic poly-vascular disease have a higher CV risk than patients with single vascular disease, and in both groups liraglutide consistently reduced major CV outcomes.

Moderate and severe malnutrition in HF patients, assessed with simple malnutrition scores, was associated with higher all-cause mortality.

Patients with hypertension with low platelet counts and high total homocysteine levels, which may promote platelet adherence, had the highest risk of first stroke, and this risk was reduced with folic acid treatment.