Physicians' Academy for Cardiovascular Education

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ACC 2020 ▼AHA 2019 ▼Covid-19 ▼Covid-19, ACE2, RAASi ▼Diabetes & CVD ▼EAS 2019 ▼ESC 2019 ▼ESC Diabetes guidelines 2019 ▼ESC/EAS Guidelines dyslipidaemias 2019 ▼HFpEF: The essentials to know ▼Kidney disease & CVD ▼LDL-c Key Lessons ▼

C-Reactive Protein, Inflammation and Atherosclerosis

Jan. 24, 2016

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4 Things a cardiologist should know about triglycerides

Reducing triglycerides in REDUCE-IT

10' education - Feb. 11, 2020 - Prof. Deepak Bhatt, MD - Online CME

The spectrum of triglyceride-containing lipoproteins

10' education - Feb. 4, 2020 - Jorge Plutzky, MD - Online CME

How can triglycerides increase CV risk?

10' education - Jan. 16, 2020 - Prof. Børge Nordestgaard, MD

5 Things a cardiologist should know about diabetes

Slide Curriculum: Diabetes and cardiology

Slides (curriculum) - July 24, 2018

PACE Special: 5 Things a cardiologist should know about diabetes

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Hypoglycemia in cardiovascular medicine: why worry?

10' education - Mar. 7, 2018 - Prof Guntram Schernthaner - Vienna, Austria - Online CME

ACS

P2Y12i monotherapy reduces net adverse clinical events in ACS patients undergoing PCI with DES

News - Apr. 9, 2020

P2Y12i monotherapy after 3 months DAPT reduces bleeding after complex PCI

News - Apr. 7, 2020

Stopping with aspirin after 3 months DAPT is safe in a wide range of patients

3' education - Apr. 2, 2020 - Prof. Freek Verheugt, MD

Atherosclerosis

Higher frequency of coronary atherosclerotic plaques in patients with genetically confirmed FH

Literature - July 7, 2020 - Pang J et al., - Atherosclerosis. 2020.

Risk of ASCVD gradually increases with increasing SBP levels starting from 90 mmHg

Literature - July 6, 2020 - Whelton SP et al. - JAMA Cardiol. 2020.

Similar BP reductions after renal denervation across high-risk subgroups and ASCVD risk scores

Literature - June 25, 2020 - Mahfoud F et al., - J Am Coll Cardiol. 2020.

Atrial fibrillation

No increased risk of stroke in AF patients without CV comorbidities

Literature - June 18, 2020 - Singleton MJ et al., - J Am Heart Assoc. 2020

AF associated with increased CV and total mortality in East Asian HFpEF patients

Literature - May 6, 2020 - Son MK, et al. - Heart. 2020

Oral anticoagulant monotherapy reduces bleeding in AF patients after TAVI

3' education - Mar. 30, 2020 - Dr. Jur ten Berg, MD, PhD - ACC 2020

BET Inhibition

Effect of BET inhibition on CV outcomes in ACS and diabetes patients

10' education - Dec. 9, 2019 - Prof. Kausik Ray, MD

Primary endpoint not met for BET inhibitor in phase 3 trial

News - Sep. 30, 2019

BET inhibition, an epigenetic pathway: How could BET inhibition modulate atherothrombotic risk?

10' education - Sep. 30, 2019 - Prof. Wouter Jukema

Covid-19

Expert Position Paper on conducting HF clinical trials in the COVID-19 era

News - June 17, 2020

Health professionals report decrease in STEMI admissions since COVID-19 outbreak

Literature - June 15, 2020 - Pessoa-Amorim G et al., - Eur Heart J Qual Care Clin Outcomes. 2020.

Prevention and management of CVD in diabetes patients in the COVID-19 era

News - June 2, 2020

CV Inflammation

Pro-inflammatory activation of monocytes by elevated Lp(a) is reversible by potent Lp(a)-lowering

Literature - May 12, 2020 - Stiekema LCA et al., - Eur Heart J. 2020

High CV risk in atherosclerosis patients with highest levels of inflammatory biomarkers and LDL-c

Literature - Apr. 28, 2020 - Ridker PM, et al. - Eur Heart J 2020

PCSK9 siRNA does not affect inflammation measures or hematological parameters

Literature - Apr. 28, 2020 - Landmesser U et al., - Cardiovasc Res. 2020.

CVRM

The growing global challenge of CV risk

5' education - Jan. 15, 2020 - Thomas Gaziano, MD

Persons with NAFLD are not automatically at high risk of acute MI or stroke

Literature - Nov. 4, 2019 - Alexander M et al, - BMJ 2019

Not only weight loss, but also maintaining a lower weight is important for a good CV risk profile

Literature - Oct. 14, 2019 - Berger SE et al., - J Am Heart Assoc. 2019

Diabetes

Diabetes and CKD: is it all about managing glucose?

10' education - July 1, 2020 - Prof. Melanie Davies, MD

DKD and CV risk: What is the potential of targeting GLP-1?

10' education - June 16, 2020 - Prof. Erik Stroes, MD

Icosapent ethyl reduces both first and total CV events in diabetes patients

News - June 16, 2020

Diabetes & CVD

Diabetes and CKD: is it all about managing glucose?

10' education - July 1, 2020 - Prof. Melanie Davies, MD

SGLT2i reduces patient-reported HF symptom burden in HFrEF

News - June 30, 2020

Beneficial effect of SGLT2i in HFrEF independent of use of diuretic therapy

News - June 23, 2020

Epigenetics in CVD

Effect of BET inhibition on CV outcomes in ACS and diabetes patients

10' education - Dec. 9, 2019 - Prof. Kausik Ray, MD

BET inhibitor therapy did not meet primary endpoint of reducing MACE in post-ACS patients with T2DM

News - Nov. 17, 2019

Clinical update on BET inhibition: The patient profile that may benefit from BET inhibition

10' education - Aug. 31, 2019 - Prof. Kausik Ray, MD

ESC Diabetes guidelines 2019

Slides: 2019 ESC guidelines on diabetes, pre-diabetes and cardiovascular diseases - Expert insights and rationale

Slides (presentation) - Oct. 7, 2019 - Prof Francesco Cosentino, MD, Stockholm, Sweden - CME symposium held during ESC 2019

The 2019 ESC/EASD diabetes guidelines: a major paradigm shift in the management of T2DM

10' education - Sep. 30, 2019 - Paris, France - Prof. Francesco Cosentino, MD

New ESC/EASD Guidelines on diabetes no longer regard metformin as first-line therapy

News - Sep. 3, 2019

ESC/EAS Guidelines dyslipidaemias 2019

LDL-c targets in the ESC/EAS dyslipidaemia guidelines in a nutshell

10' education - Oct. 4, 2019 - Prof. Brian Ference, MD

Slides: LDL-c targets in the ESC/EAS dyslipidaemia guidelines in a nutshell

Slides (presentation) - Sep. 9, 2019 - ESC Paris, France - Prof. Brian A. Ference, M.D, University of Cambridge, United Kingdom - CME symposium held during ESC 2019

Rationale for the lower LDL-c targets in the 2019 ESC/EAS Dyslipidemia Guidelines

5' education - Sep. 9, 2019 - Paris, France - Prof. François Mach

Expert Meeting GLP-1, CVD & T2DM

Translation of novel approaches in CVD & diabetes to clinical practice

10' education - Mar. 22, 2018 - John Deanfield, Francesco Cosentino, Filip Knop - Online CME

Novel diabetes drugs in clinical management: Extending the opportunities

10' education - June 5, 2018 - Stefano Taddei, Cees Tack, Massimo Volpe - Online CME

Clinical trials in diabetes and CVD: What did we learn?

10' education - Mar. 22, 2018 - Filippo Crea, Angelyn Bethel, Eduard Montanya - Online CME

Familial Hypercholesterolemia

Higher frequency of coronary atherosclerotic plaques in patients with genetically confirmed FH

Literature - July 7, 2020 - Pang J et al., - Atherosclerosis. 2020.

Familial Hypercholesterolemia: Why and how to screen?

10' education - June 30, 2020 - Prof. Kees Hovingh, MD, PhD

Incorporation of genetic testing increases rates of diagnosis for FH

Literature - June 29, 2020 - Brown EE et al., - J Clin Lipidol. 2020.

GLP-1 RA & CVD

GLP-1RA therapy results in smaller decline of eGFR

News - June 9, 2020

ESC Congress 2020 Amsterdam goes digital

News - May 6, 2020

GLP-1RA reduces BMI standard deviation score in adolescents with obesity

Literature - Apr. 28, 2020 - Kelly AS et al., - N Engl J Med. 2020.

Heart Failure

Improving outcomes for patients following an admission with ADHF

15' education - July 7, 2020 - Prof. Mark Petrie, MD and Klaus Witte, MD

LVEF deterioration into midrange levels increases risk of adverse outcomes in HFmrEF

Literature - July 2, 2020 - Brann A et al., - JAMA Cardiol. 2020.

Diabetes and CKD: is it all about managing glucose?

10' education - July 1, 2020 - Prof. Melanie Davies, MD

HFpEF: The essentials to know

HFpEF: Current and future clinical approaches to manage HFpEF

10' education - Aug. 27, 2018 - Burkert Pieske, MD - Berlin, Germany - Online CME

Slides: HFpEF: What are the most likely pathophysiological mechanisms involved in the disease

Slides (presentation) - Aug. 27, 2018 - Carolyn Lam, MD - Singapore

HFpEF: How to diagnose

10' education - Aug. 27, 2018 - Barry Borlaug - Rochester, MN, USA - Online CME

Hypertension

Risk of ASCVD gradually increases with increasing SBP levels starting from 90 mmHg

Literature - July 6, 2020 - Whelton SP et al. - JAMA Cardiol. 2020.

Similar BP reductions after renal denervation across high-risk subgroups and ASCVD risk scores

Literature - June 25, 2020 - Mahfoud F et al., - J Am Coll Cardiol. 2020.

Earlier onset of hypertension associated with higher risk for mortality

Literature - June 23, 2020 - Wang C et al., - J Am Coll Cardiol. 2020.

Inflammation Expert Opinions

Ultime notizie sulla terapia: Un farmaco anti-infiammatorio riduce eventi cardiovascolari maggiori

5' education - Aug. 27, 2017 - ESC 2017, Barcelona, Spain

Breakthrough therapy: Anti-inflammatory drug can affect important CV outcomes

5' education - Aug. 27, 2017 - ESC 2017, Barcelona, Spain

Clinical implications of inhibiting inflammation as risk factor for progression of CVD

5' education - Aug. 27, 2017

Invest in your arteries

Estimating CV risk and treatment benefit

10' education - June 12, 2018 - Prof. Frank Visseren - Utrecht, The Netherlands - Online CME

Importance of hypertension in CVD prevention

10' education - June 12, 2018 - Prof. Richard Hobbs - Oxford, UK - Online CME

The role of lipids in CVD prevention: Lessons learned about statins

10' education - June 6, 2018 - Prof. Kees Hovingh - Amsterdam, The Netherlands - Online CME

Kidney disease & CVD

Diabetes and CKD: is it all about managing glucose?

10' education - July 1, 2020 - Prof. Melanie Davies, MD

Similar BP reductions after renal denervation across high-risk subgroups and ASCVD risk scores

Literature - June 25, 2020 - Mahfoud F et al., - J Am Coll Cardiol. 2020.

The cardiorenal connection and diabetes: Exploring intervention by SGLT2i

10' education - June 23, 2020 - Maria Rosa Costanzo, MD

Lipids

Higher frequency of coronary atherosclerotic plaques in patients with genetically confirmed FH

Literature - July 7, 2020 - Pang J et al., - Atherosclerosis. 2020.

Familial Hypercholesterolemia: Why and how to screen?

10' education - June 30, 2020 - Prof. Kees Hovingh, MD, PhD

Incorporation of genetic testing increases rates of diagnosis for FH

Literature - June 29, 2020 - Brown EE et al., - J Clin Lipidol. 2020.

Lp(a)

Phase 2 dose-finding study with PCSK9i in children and adolescents with HeFH

Literature - June 18, 2020 - Daniels S et al., - J Clin Lipidol. 2020.

Treatment goals for LDL-c-lowering and emerging evidence for the importance of Lp(a)

10' education - May 26, 2020 - Prof. J. Wouter Jukema, MD - Leiden, The Netherlands

Pro-inflammatory activation of monocytes by elevated Lp(a) is reversible by potent Lp(a)-lowering

Literature - May 12, 2020 - Stiekema LCA et al., - Eur Heart J. 2020

PCSK9

Phase 2 dose-finding study with PCSK9i in children and adolescents with HeFH

Literature - June 18, 2020 - Daniels S et al., - J Clin Lipidol. 2020.

PCSK9i reduces CV events in patients with recent MI

Literature - May 28, 2020 - Gencer B et al., - JAMA Cardiol. 2020.

Treatment goals for LDL-c-lowering and emerging evidence for the importance of Lp(a)

10' education - May 26, 2020 - Prof. J. Wouter Jukema, MD - Leiden, The Netherlands

Pulmonary Arterial Hypertension

Pulmonary Arterial Hypertension: Key questions addressed

Online-CME - This course consists of 3 separate lectures

Why cardiologists should be more interested in PAH

3' education - Mar. 9, 2018 - VBWG at ACC, Orlando, FL, USA - Prof. Mardi Gomberg-Maitland, Falls Church, VA, USA - Online CME

Novel insights in the management and prognosis of pulmonary hypertension

5' education - Aug. 29, 2017 - ESC 2017, Barcelona, Spain - Prof Nazzareno Galiè - Bologna, Italy

Stroke

No increased risk of stroke in AF patients without CV comorbidities

Literature - June 18, 2020 - Singleton MJ et al., - J Am Heart Assoc. 2020

Health professionals report decrease in STEMI admissions since COVID-19 outbreak

Literature - June 15, 2020 - Pessoa-Amorim G et al., - Eur Heart J Qual Care Clin Outcomes. 2020.

P2Y12i monotherapy reduces risk of myocardial infarction compared to aspirin monotherapy

Literature - June 9, 2020 - Chiarito M et al., - The Lancet. 2020.

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