Physicians' Academy for Cardiovascular Education

Changing views on mechanisms of atherosclerosis

10' education - Feb. 12, 2016 - Boston, MA, USA - Prof. Peter Libby (Boston, MA, USA)

Prof. Peter Libby (Boston, MA, USA) discusses how views on mechanisms of ACS have changed over time and how traditional thoughts on plaque composition and vulnerability are now challenged. He proposes a new mechanism of coronary thrombosis that may cause ACS.

Video navigation menu

  • Plaque rupture leading to ACS 00:27
  • Challenges to the vulnerable plaque concept 01:43
  • Athero Express study: Changes in atherosclerotic plaque composition 04:40
  • Effects of intensive statin treatment on human atherosclerotic plaques 06:04
  • What mechanisms beyond plaque rupture may contribute to the residual burden of events? 07:30
  • Superficial erosion of the endothelial layer, a mechanism of coronary thrombosis 07:58


Peter Libby, MD - Brigham and Women's Hospital, Mallinckrodt Professor of Medicine at Harvard Medical School, Boston, MA, USA

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