Unfavourable effect of electronic cigarette smoking similar to tobacco smokingVlachopoulos C et al. JACC 2016
Electronic Cigarette Smoking Increases Aortic Stiffness and Blood Pressure in Young Smokers
Vlachopoulos C, Ioakeimidis N., Abdelrasoul M, et al.
JACC. Volume 67(23): 2802–2803. doi:10.1016/j.jacc.2016.03.569
BackgroundElectronic cigarettes (EC) have been advocated as a less harmful alternative to tobacco cigarettes (TC). Smoking TC increases aortic stiffness and blood pressure (BP) .
This research letter compared the effects of EC and TC smoking on aortic stiffness and BP. 24 smokers (aged 30+8 years) without other CV risk factors were measured in four separate occasions: 1: TC over 5 min, 2: EC over 5 min, 3: EC for a period of 30 min, and 4: nothing for 60 min. Nicotine delivery rate is lower and slower with EC than with TC. Aortic stiffness was assessed with carotid-femoral pulse-wave velocity (PWV).
- Heart rate increased significantly in TC (4.0 beats/min after 5 min, P<0.05) and EC-30 (3.1 beats/min after 30 min) sessions, but not after EC-5 (P=0.57).
- Systolic BP increased significantly in TC and EC sessions, without a significant difference between the two forms of smoking.
- PWV increased by 0.44 m/s as compared with baseline, immediately after the end of TC smoking, and remained elevated throughout the measurement period of 60 min.
- A significant PWV increase by 0.19 m/s was seen after 15 min in response to EC-5. EC-30 smoking elicited a stronger and prolonged PWV increase, with the peak immediately after the end of smoking, by 0.36 m/s.
- EC-30 yielded a PWV increases similar to that of TC smoking throughout the study period (F=0.268, P=0.615), while EC-5 led to a less potent PWV increase as compared with TC (F=4.425, P=0.005).
ConclusionThese data show that smoking of an electronic cigarette (30 min) induces an unfavourable effect on aortic stiffness and BP, similar to smoking of tobacco cigarettes. The effect of 5 min of EC smoking on aortic stiffness is weaker and delayed as compared to TC.
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1. Vlachopoulos C, Kosmopoulou F, Panagiotakos D, et al. Smoking and caffeine have a synergistic detrimental effect on aortic stiffness and wave reflections. J Am Coll Cardiol 2004;44:1911–7