Physicians' Academy for Cardiovascular Education

Safety of NOAC instead of aspirin in ACS patients

Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial

Presented at ACC.17 by Magnus E Ohman

News - Mar. 18, 2017

Main results


A safety study of rivaroxaban versus aspirin, on top of P2Y12 therapy in ACS patients, showed that this dual antithrombotic regimen had a similar risk of clinically significant bleeding. These findings suggest that substituting aspirin with low-dose rivaroxaban is a safe therapeutic option in this setting.


Our coverage of ACC.17 is based on the information provided during the congress.

The accompanying article was published today in The Lancet

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