Physicians' Academy for Cardiovascular Education

Paroxysmal AF associated with worse clinical outcomes than persistent AF

Paroxysmal atrial fibrillation is associated with worse clinical outcomes than persistent/ permanent atrial fibrillation in patients with heart failure and reduced ejection fraction

Presented at ACC.17 by JJV McMurray

News - Mar. 23, 2017

Main results

Conclusion

Paroxysmal, but not persistent/permanent AF, was associated with a higher risk of the composite outcome of HF hospitalisation or CV death, even after adjustment for other prognostic variables, including NT proBNP. This finding was driven by an elevated risk of HF hospitalisation. Paroxysmal AF was also associated with a higher adjusted risk of stroke, but persistent/permanent AF was not. New-onset AF conferred the greatest risk of all, since it was associated with a higher risk of HF hospitalisation, death and stroke. These data suggest that new-onset AF should prompt immediate consideration of anticoagulant therapy.

Disclosures

Our coverage of ACC.17 is based on the information provided during the congress.

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