Physicians' Academy for Cardiovascular Education

New meta-analysis on statin use in elderly

Primary Prevention With Statin Therapy in the Elderly: New Meta-Analyses from the Contemporary JUPITER and HOPE-3 Randomized Trials

Literature - Ridker PM, Lonn E, Paynter NP, et al. - Circulation. 2017; published online ahead of print

Main results

Conclusion

The meta-analysis of elderly subgroup data in the JUPITER and HOPE-3 studies provide some insights in statin use for the primary prevention of the elderly, however, it also leaves critical questions unanswered that are relevant for clinical practice. For example, benefits should be weighed against the potential for a modest impact on longevity and personal preferences must be taken into account, although benefits are consistent above and below the age of 70.

References

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