Physicians' Academy for Cardiovascular Education

SGLT-2 inhibitor did not decrease risk of stroke in diabetic patients

Empagliflozin and Cerebrovascular Events in Patients With Type 2 Diabetes Mellitus at High Cardiovascular Risk

Literature - Zinman B, Inzucchi SE, Lachin, ScD JM, et al. - Stroke. 2017;48: published online ahead of print

Main results


In T2DM patients at high cardiovascular risk enrolled in the EMPA-REG OUTCOME trial, empagliflozin, when compared with placebo, was not associated with either a reduction or an increase in the risk of cerebrovascular events.


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