Physicians' Academy for Cardiovascular Education

Intensive BP reduction beneficial for prevention of acute decompensated HF

Effect of Intensive Blood Pressure Treatment on Heart Failure Events in the Systolic Blood Pressure Reduction Intervention Trial

Literature - Upadhya B, Rocco M, Lewis CE, et al, for the SPRINT Research Group - Circ Heart Fail. 2017;10:e003613

Main results


In all predetermined subgroups of patients at high risk for cardiovascular events in the SPRINT trial, targeting an SBP of <120 mmHg, as compared with <140 mmHg, significantly reduced the risk of developing ADHF by 36%. ADHF patients had a significantly higher risk for death and cardiovascular events. These findings highlight the importance of intensive BP reduction to prevent ADHF.


Show references

Find this article online at Circ. Heart Fail.

Share this page with your colleagues and friends: