Higher fruit and vegetable intake associated with less PAD
Greater Frequency of Fruit and Vegetable Consumption Is Associated With Lower Prevalence of Peripheral Artery DiseaseLiterature - Heffron SP, Rockman CB, Adelman MA, et al. - Arterioscler Thromb Vasc Biol. 2017;37: published online ahead of print
- Increasing age, female gender, non-sedentary lifestyle, increasing income, and frequent consumption (most days of the week) of fish, nuts, and red meat were positively associated with the daily consumption of F&V.
- Non-white race, current or former smoking, being currently unmarried, and frequent consumption of fast food were inversely associated with daily intake of at least 3 servings of F&V.
- After multivariable adjustment for age, gender, race/ethnicity, and clinical risk factors, there was an inverse association between F&V intake and the prevalence of PAD (P for trend <0.001).
- Additional adjustment for income and dietary components other than F&V resulted in minimal attenuation of the association (P for goodness of fit = 0.12).
- When adjusted analyses were stratified by gender, the association persisted, but was slightly more pronounced in men (P<0.01).
- The stratification of the sample by cigarette smoking status (current, former, and never) showed that the inverse association of increasing F&V consumption with PAD was limited to subjects who currently or formerly smoked.
- Among all subjects with abnormal ankle brachial index (ABI), 73.2% had an ABI of 0.9–0.7, 19.7% had an ABI of 0.7–0.5, and 7.1% had an ABI <0.5.
- The inverse association with F&V intake was stronger with decreasing ABI in both crude and multivariable-adjusted models.
In a large community-based study, there was an inverse association between F&V consumption and prevalent PAD. These results suggest that increasing F&V consumption may be important in PAD prevention.