Physicians' Academy for Cardiovascular Education

Higher fruit and vegetable intake associated with less PAD

Greater Frequency of Fruit and Vegetable Consumption Is Associated With Lower Prevalence of Peripheral Artery Disease

Literature - Heffron SP, Rockman CB, Adelman MA, et al. - Arterioscler Thromb Vasc Biol. 2017;37: published online ahead of print


Guidelines recommend the consumption of at least 4.5 cups of fruits and vegetables (F&V) combined daily, mainly based on the F&V associations with a reduced risk of cancer and overall mortality [1-3]. Less robust data are available on the F&V associations with CV disease [4,5].

In this large community-based study, the association between F&V consumption and the presence of Peripheral Artery Disease (PAD) was assessed in approximately 3.7 million American adults (mean age 64.1+10.2 years, 64.1% female, 89.1% white). The study population consisted of self-referred individuals who underwent vascular screening tests at Life Line Screening Inc. between 2003 and 2008. Before undergoing anthropometric measures, individuals completed an extensive questionnaire regarding demographics, risk factors, medical history, physical activity and dietary intake.

Main results


In a large community-based study, there was an inverse association between F&V consumption and prevalent PAD. These results suggest that increasing F&V consumption may be important in PAD prevention.


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