Physicians' Academy for Cardiovascular Education

Long-acting statins are also effective when taken in the morning

Effects of Morning Versus Evening Statin Administration on Lipid Profile: A Systematic Review and Meta-Analysis

Literature - Awad K, Serban MC, Penson P, et al. - Journal of Clinical Lipidology 2017; published online ahead of print

Main results


Short-acting statins are significantly more effective in lowering LDL-C and TC when they are administered in the evening, rather than the morning, whereas long-acting statins had a nearly equivalent efficacy irrespective of timing of administration during the day, with the exception of a small but statistically significant effect on LDL-C. These findings confirm that short-acting statins should be taken in the evening and the authors suggest that long-acting statins can also be taken in the morning, if this facilitates patient compliance.


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Find this article online at Journal of Clinical Lipidology

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