Regular activity breaks improve postprandial triglyceride response
Regular activity breaks combined with physical activity improves postprandial plasma triglyceride , non-esterified fatty acid and insulin responses in healthy, normal weight adults: a randomized crossover trialLiterature - Homer AR, Fenemor SP, Perry TL, et al. - Journal of Clinical Lipidology, 2017; June 19, Epub ahead of print
- Whereas fasting concentrations on day 2 for non-esterified fatty acid (NEFA), glucose, and insulin were not significantly different between interventions, these of triglycerides were (SIT: 87.22 mg/dL, SIT+PA: 83.66 mg/dL, RAB: 85.44 mg/dL, RAB+PA: 79.21 mg/dL, P=0.005).
- More specifically, RAB+PA resulted in lower fasting triglycerides compared to all other 3 interventions (mean difference compared to SIT -8.9, SD -16.02 to -2.67, P=0.008, compared to SIT+PA -6.23, SD -13.35 to 0.00, P=0.054, compared to RAB -10.68, SD -17.80 to -4.45, P=0.002).
- Looking at the total AUCs the overall effect of intervention at day 2 was significant for triglycerides (P=0.008), NEFA (P<0.001) and insulin (P<0.001), but not for glucose (P=0.290).
- More specifically, RAB and RAB+PA reduced triglyceride response with 7% and 11% respectively, when compared to SIT and RAB+PA reduced it by 10% when compared to SIT+PA. Moreover, RAB and RAB+PA attenuated the postprandial suppression of NEFA by 23% and 15% respectively, when compared to SIT. Regarding insulin, both interventions with PA reduced the response with 13-15%, compared to SIT.
- Looking at the incremental AUCs, the overall effect of intervention was not significant for NEFA, glucose or insulin, but was for triglycerides (SIT: 175.33 mg/dL, SIT+PA: 184.23 mg/dL, RAB: 141.51 mg/dL and RAB+PA: 150.41 mg/dL, P=0.002).
When measured 1 full day after breaks or PA, postprandial triglyceride response is attenuated by breaks of 2 minutes with regular activity. This is further enhanced when combining regular breaks with PA of 30 minutes of continuous walking, which also improves insulinemic responses.