Physicians' Academy for Cardiovascular Education

Single 24-hour urine collection does not suffice to estimate an individual’s sodium intake

Use of a Single Baseline Versus Multi-Year 24-Hour Urine Collections for Estimation of Long-Term Sodium Intake and Associated Cardiovascular and Renal Risk

Literature - Olde Engberink RHG, van den Hoek TC, van Noordenne ND, et al., - Circulation. 2017; Originally published June 27, 2017.

Main results


This study shows that, on a population level, a single baseline measurement and repetitive follow-up 24-hour urine sodium measurements lead to similar estimates of sodium intake. Estimations of individual sodium intake, however, differ significantly. This affected the association between sodium intake and long-term outcomes.

These data indicate that a single 24-hour urine sodium collection can be used to estimate average sodium intake in a population, but is imprecise for estimation of long-term individual sodium intake, and thus inadequate to study the relation between sodium intake and long-term CV or renal outcome.

Imprecise estimation of sodium intake at baseline has consequences for classification of subjects as low, moderate or high sodium consumers. Only when 1- and 5-year estimates were used, a positive correlation between sodium intake and long term CV risks was seen.


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Find this article online at Circulation

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