Physicians' Academy for Cardiovascular Education

Higher risk of recurrent stroke after early statin discontinuation

Utilization of Statins Beyond the Initial Period After Stroke and 1-Year Risk of Recurrent Stroke

Literature - Lee M, Saver JL, Wu Y-L, et al. - J Am Heart Assoc. 2017;6:e005658

Main results

Compared with the statin-maintained group, the discontinuation of statins was associated with higher risks of:


The discontinuation of statin therapy 3 to 6 months after an index ischemic stroke event, was associated with a higher risk of recurrent stroke within 1 year after statin discontinuation. These findings suggest that stroke patients should not discontinue statin therapy, unless there is a serious reason for doing so.


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