Physicians' Academy for Cardiovascular Education

SBP variability is associated with clinical outcomes in atrial fibrillation patients

Systolic Blood Pressure Visit-to-Visit Variability and Major Adverse Outcomes in Atrial Fibrillation: The AFFIRM Study (Atrial Fibrillation Follow-Up Investigation of Rhythm Management)

Literature - Proietti M, Romiti GF, Olshansky B, et al. - Hypertension 2017, published online ahead of print

Main results

SBP-VVV and quality of anticoagulation control

Follow-Up and Survival Analysis

Multivariate Analyses


In the AFFIRM study, SBP-VVV was inversely associated with the quality of anticoagulation control in AF patients, and increasing SBP-VVV was associated with a higher risk of major adverse clinical events. These results suggest that reducing SBP-VVV and improving the quality of anticoagulation control might be of benefit for AF patients.


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