Physicians' Academy for Cardiovascular Education

hsCRP levels predict CV outcomes in type 2 diabetic patients post-ACS

High-sensitivity C-reactive Protein, Low-Density Lipoprotein Cholesterol, and Cardiovascular Outcomes in Patients with Type 2 Diabetes in the EXAMINE (Examination of Cardiovascular Outcomes With Alogliptin Versus Standard of Care) Trial

Literature - Hwang YC, Morrow DA, Cannon CP, et al. - Diabetes Obes Metab. 2017; published online ahead of print

Main results


In T2DM patients at high CV risk with a recent ACS, there is a significant association between baseline hsCRP values and future CV outcomes, independent and additive to the achieved LDL-c level. These results suggest that the measurement of hsCRP levels, in addition to LDL-c, in these patients may be useful to assess their residual CV risk.


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