Physicians' Academy for Cardiovascular Education

Patients with severe hypertriglyceridemia benefit from omega-3 carboxylic acids 2 g/day

Omega-3 carboxylic acids in patients with severe hypertriglyceridemia: EVOLVE II, a randomized, placebo-controlled trial

Literature - Stroes ESG, Susekov AV, de Bruin TWA, et al. - J of Clin Lipidol 2017; printed online ahead of print

Main results


Patients with SHTG treated with OM3-CA 2 g daily had a statistically significant reduction in TG and non-HDL-c concentrations compared with those treated with olive oil 2 g daily. Patients with qualifying TG concentrations > 885 mg/dL (> 10 mmol/L) showed a larger TG reduction than those in the overall study population. These findings suggest that OM3-CA may be useful for the prevention of acute pancreatitis and CVD in these patients.


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Find this article online at J Clin Lipidol 2017

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