Physicians' Academy for Cardiovascular Education

Can LDL go too low? Lessons from 25 years of cholesterol lowering

10' education - Oct. 26, 2017 - Boston, MA, USA - Dr. Robert Giugliano - Brigham & Women's Hospital, Boston, USA

Dr. Robert Giugliano summarizes what we have learned over the past decades about the effectiveness and safety of reducing LDL-c to very low values.

Video navigation menu

  • Lessons from two decades of cholesterol treatment 00:14
  • Safety of very low LDL-c values 01:31
  • FOURIER: effectiveness/safety per baseline LDL-c 03:41
  • Effectiveness/safety of very low LDL-c values with evolocumab 06:18
  • Conclusion after 25 years of LDL-c reduction: Lowest is best in secondary prevention 10:30

Educational information

This video was recorded on October 26, 2017 in Boston and is a shortened version of the presentation that Dr. Giugliano gave there during the educational program 'Advances in Lipid Management and Cardiovascular Risk Reduction: New Horizons for 2018'


Dr. Robert P. Giugliano is a cardiovascular medicine specialist at BWH and an associate professor of medicine at Harvard Medical School. In addition, he is a senior investigator of BWH’s Thrombolysis in Myocardial Infarction (TIMI) Study Group.


This recording was independently developed under auspices of PACE-cme. The views expressed in this recording are those of the individual presenter and do not necessarily reflect the views of PACE-cme. PACE-cme did not receive financial support for the production of this recording.

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