Physicians' Academy for Cardiovascular Education

Omega-3 fatty acid supplements do not reduce CV risk

Associations of Omega-3 Fatty Acid Supplement Use With Cardiovascular Disease Risks Meta-analysis of 10 Trials Involving 77917 Individuals

Literature - Aung T, Halsey J, Kromhout D, et al - JAMA Cardiol 2018; published online ahead of print

Main results


A large meta-analysis showed that omega-3 FA supplementation is not associated with a reduction in fatal and non-fatal CHD and other major vascular events. These data do not support the recommendation to use of ~1 g/d of omega-3-FA supplements for the prevention of CV events. It will be interesting to see whether higher doses of omega-3 FA (3-4 g/d) may have significant effects on risk of major vascular events.


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Find this article online at JAMA Cardiol 2018

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