Physicians' Academy for Cardiovascular Education

Higher childhood BMI associated with increased risk of cardio-metabolic disease later in life

Childhood BMI and Adult Type 2 Diabetes, Coronary Artery Diseases, Chronic Kidney Disease, and Cardiometabolic Traits: A Mendelian Randomization Analysis

Literature - Geng T, Smith CE, Li C, et al. - Diabetes Care 2018; published online ahead of print

Main results

A one-SD increase in childhood BMI was causally associated with a:


A genetic predisposition to higher childhood BMI was associated with an increased risk of T2DM, CAD, and cardio-metabolic traits in adult life. These results show that there is a substantial public health impact of childhood BMI modification.


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Find this article online at Diabetes Care 2018

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