Self-applied ECG patch improves the rate of AF diagnosis
A Digital End-to-End, Nationwide, Pragmatic Trial of Screening for Undiagnosed Atrial Fibrillation Within a Health Insurance System Using a Self-Applied ECG Patch: Primary Results of the mHealth Screening to Prevent Strokes (mSToPS) Trial
Presented at ACC.18 by Steven Steinhubl (La Jolla, CA, USA)News - Mar. 11, 2018
- 1- year new diagnosis of AF was 6.3% in 1738 participants who were actively monitored compared to 2.3% in 3476 matched controls (unadj OR 2.8; 95%CI:2.1-3.7, P<0.0001 and adj OR 3.0; 95%CI:2.2-4.0, P<0.0001).
- Median total AF burden during monitoring was 0.9% and median duration of longest AF period was 185.5 min (92.8% >5 minutes, 37.7% >6 hours).
- Active monitoring was associated with increased initiation of anticoagulation therapy compared to routine care (5.4% vs. 3.4%, P=0.0004)
- No differences in clinical outcomes (stroke, myocardial infarction, systemic thromboembolism) between the actively monitored participants and matched controls were observed.
In a digital clinical trial with patient-generated data, use of a wearable ECG patch showed an improvement in the rate of AF diagnosis compared to routine care. Follow-up is needed to understand the clinical impact of ECG monitoring.
In a press release dr. Steinhubl said: “In most cases, the only currently recommended method is to feel someone’s pulse or check an ECG for 30 seconds during a routine doctor’s visit. Based on our data, individuals have very short episodes of AF that would make it very difficult to catch in the way we routinely look for it today.”
Our coverage of ACC.18 is based on the information provided during the congress.