Physicians' Academy for Cardiovascular Education

What are the key mechanisms of CV benefit of novel diabetes drugs?

Expert Meeting on CVD & T2DM

10' education - May 1, 2018 - Lina Badimon, Jochen Seufert, Naveed Sattar - Online CME

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  • What are the mechanisms underlying the CV benefits observed with GLP-1 receptor agonists? 0:40
  • Based on the CV outcomes trials with GLP-1 RAs, it is not clear yet whether there is a class effect 3:38
  • SGLT2 inhibitors: which mechanisms can explain the CV benefit ? 4:03
  • It is important to consider the types of patients included in trials when interpreting the results 6:13
  • The trial design affects what kind of data and insights can be obtained from it 8:38
  • The unexpected results with novel antidiabetic drugs raise questions on the pathophysiology of T2DM that deserve further study 9:13

Educational information

This video was recorded during a two-day expert meeting among cardiologists and endocrinologists/internists, focussing on the topic of 'Exploring the role of GLP-1 RA in the management of CVD & T2DM'. This video reflects the discussion in the second of 5 sessions.


Prof. Lina Badimon - cardiologist, Hospital Santa Creu and San Pau, Barcelona, Spain

Prof. Jochen Seufert - endocrinologist, Universitätsklinikum, Freiburg, Germany

Prof. Naveed Sattar -endocrinologist, University of Glasgow, United Kingdom


This recording was independently developed under auspices of PACE-cme. The views expressed in this recording are those of the individual presenters and do not necessarily reflect the views of PACE-cme.


Funding for the Expert Meeting was provided by an unrestricted educational grant from Novo Nordisk. The sponsor did not attend and influence the meeting or the video recording.

Also see: What is the science driving CVD and T2DM? Also see: Novel diabetes drugs in clinical management: Extending the opportunities


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