Physicians' Academy for Cardiovascular Education

CV health scores are declining and CVD rates are increasing in the US

Twenty-Year Trends in the American Heart Association Cardiovascular Health Score and Impact on Subclinical and Clinical Cardiovascular Disease: The Framingham Offspring Study

Literature - Enserro DM, Vasan RS, Xanthakis V, et al. - J Am Heart Assoc. 2018;7:e008741.

Introduction and methods

Although CV mortality has decreased, CVD still causes high health care costs in the US. The ideal CV health, defined by the American Heart Association (AHA), is associated with decreased subclinical and incident CVD [1-3]. However, the temporal trend in ideal CV health of Americans is not known, and it might have decreased during the past 20 years, partly due to increasing rates of obesity.

In this analysis of a large community-based sample from the Framingham Heart Study [4], temporal trends in ideal CV health were evaluated, and their association with subclinical/overt CVD and death were assessed. 4139 Framingham Offspring cohort participants attending at least one examination cycle between 1991 and 2008 were enrolled. The exclusion criteria included prevalent CVD, serum creatinine levels ≥2 mg/dL, BMI <18.5 kg/m2, missing CV health score components, and extremely high lipid values. After application of the exclusion criteria, the study sample consisted of 3460 participants.

The (AHA) CV Health Score was calculated based on 7 variables (BMI, smoking status, physical activity, diet, fasting glucose concentrations, blood pressure, and total cholesterol levels). Each variable was scored with 2 if ideal, whereas a score of 1 was given for an intermediate status and a score of 0 for a poor status. The diet was evaluated with the food frequency questionnaire, and the physical activity with a questionnaire-based index and the Paffenberger Questionnaire.

Subclinical disease was considered as a diagnosis if participants had at least one of the following: increased carotid intima media thickness or stenosis, left ventricular hypertrophy or systolic dysfunction, reduced ankle-brachial index, or microalbuminuria. The outcomes of interest were incidence of all-cause mortality or the first CV event, including stroke or transient ischemic attack, myocardial infarction, coronary insufficiency, angina pectoris, intermittent claudication, or heart failure.

Main results

Conclusion

CV health scores, as defined by the AHA, have decreased over the past 20 years among American individuals, resulting in an increased risk of developing subclinical disease and incident CVD, as well as all-cause mortality. These results suggest that there is a need to intensify public health policies and community-based efforts to improve CV health scores in the US.

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