Prof. Solomon gives a comprehensive overview of the PARAGON-HF trial and presents results of an analysis of combined data of the PARADIGM-HF and PARAGON-HF trials. With question to test your knowledge.

Prof. Pieske gives a broad overview of heart failure with mid range ejection fraction, including prevalence, etiolgies and treatment options.

Milton Packer presents findings from the two major HF trials with sacubitril/valsartan, PARADIGM-HF and PARAGON-HF, and proposes that the definition of HFrEF should be changed to EF <50%.