EAS 2021 This study showed that children with familiar hypercholesterolemia had an increased susceptibility of LDL particles to form aggregates and a reduced cholesterol efflux capacity of HDL compared to healthy children.
EAS 2021 This DA VINCI subanalysis showed that the proportion of patients achieving their risk-based LDL-c goal using the 2016 and 2019 ESC/EAS guidelines in patients on lipid lowering therapy for primary and secondary care was lower in Central- and East- Europe than in North- or West-Europe.
EAS 2021 An analysis of data from the German Lipoprotein Apheresis Registry (GLAR) from 2012-2020 demonstrated substantial lowering of MACE and major non-coronary events within two years of initiation of lipoprotein apheresis.
EAS 2021 An interim-analysis of the HEYMANS study showed that the majority of FH (both HeFH and HoFH) patients have a history of CV events and comorbidities. Initiation of evolocumab in these patients resulted in reduced LDL-c levels, maintained throughout the study.
EAS 2021 A pooled data analysis of ORION-9, 10 and 11 showed no changes in hematological and immunological biomarkers in patients with ASCVD or risk equivalent treated with inclisiran over a treatment period of 540 days.