Physicians' Academy for Cardiovascular Education

Key changes in the 2021 ESC/HFA heart failure guidelines

News - Aug. 27, 2021

Presented at the digital ESC Congress 2021, chaired by Theresa McDonagh (London, UK), Macro Metra (Brescia, Italy) and Coilin Baigent (Oxford, UK).


In the 2021 HF guidelines focus is on diagnosis and treatment of HF, not on prevention of HF. Many other guidelines address prevention of HF by management of CV risk and CV diseases. New in the development of these guidelines is the inclusion of two patient representatives in the Task Force.

Key changes to HFrEF treatment include:

Key changes to diagnosis and treatment of HFmrEF and HFpEF include:

With regard to treatment of HFpEF, recommendations in the new guidelines have largely remained unchanged. The Task Force acknowledges however that the treatment options for HFpEF are being revised at the time of publication of these guidelines.

Other new concepts in the 2021 guidelines compared with the 2016 version are:

The new guidelines were simultaneously published in Eur Heart J Watch a video by prof. Lam on the new guidelines

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