Physicians' Academy for Cardiovascular Education

EASD 2021

News from the virtual EASD 2021 congress, 27 Sept - 1 Oct.

Reduced cardiac adipose tissue by GLP-1RA in T2DM

News - Oct. 4, 2021

EASD 2021 Cardiac adipose tissue measured by CT was reduced by treatment with liraglutide compared to placebo in patients with T2DM, but this reduction was dependent on changes in weight loss.

hsCRP reduced by GLP-1RA in patients with T2DM

News - Oct. 1, 2021

EASD 2021 Using data of four semaglutide trials, this exploratory analysis showed that both subcutaneous and oral semaglutide reduced high-sensitivity CRP in patients with T2DM.

Wide distribution of 10-year and lifetime CV risk in patients with diabetes

News - Oct. 1, 2021

EASD 2021 There is a wide distribution of 10-year and lifetime CV risk in diabetes patients with and without a history of CVD. Use of SGLT2 inhibitors and GLP-1RAs was low in all groups.

GLP-1RAs reduce HbA1c, body weight and SBP regardless of background SGLT2i use

News - Sep. 29, 2021

EASD 2021 HbA1c, body weight and SBP were lowered by semaglutide and liraglutide, regardless of background SGLT2i therapy in diabetes patients, in a post hoc analysis of SUSTAIN 6.

GLP-1RA reduces risk of MACE regardless of metformin use in T2DM

Sep. 29, 2021

EASD 2021 This analysis showed that semaglutide reduced the risk of MACE compared to placebo regardless of metformin use in patients with T2DM.

Differential associations of eGFR and UACR with CVD subtypes in patients with diabetes

News - Sep. 29, 2021
In patients with diabetes, included in the Hoorn Diabetes Care System cohort, measures of kidney disease, eGFR and UACR, were differentially associated with subtypes of CVD.

EASD 2021 In patients with diabetes, included in the Hoorn Diabetes Care System cohort, measures of kidney disease, eGFR and UACR, were differentially associated with subtypes of CVD.

Improvements in two or more risk markers reduces risk of CVD and nephropathy in T2DM

News - Sep. 28, 2021

EASD 2021 This analysis showed that improvements in two or more risk markers were associated with reduced risk of expanded MACE, CV death and nephropathy in patients with T2DM.