Physicians' Academy for Cardiovascular Education

Initial AI assessment of LVEF is superior to initial sonographer assessment

News - Sep. 6, 2022

AI improves cardiologist evaluation of heart function – EchoNet-RCT: Blinded, Randomized Controlled Trial of Sonographer vs. Artificial Intelligence Assessment of Cardiac Function

Presented at the ESC congress 2022 by: David Ouyang, MD- Los Angeles, CA, USA

Introduction and methods

Echocardiography has many advantages; it is portable, involves no radiation and is inexpensive. However, the challenge with this technique is the variability in interpretation.

EchoNet-RCT is an investigator initiated study and the first blinded randomized trial of artificial intelligence (AI) in cardiology. A total of 3,495 transthoracic echocardiograms performed on adults for any clinical indication were included in the study. The echocardiograms were randomly allocated in a 1:1 ratio to initial assessment by an AI algorithm [1] or to initial assessment by the sonographer. The initial assessment was subsequently reviewed by blinded cardiologists who provided a final report of LVEF.

The primary endpoint was the proportion of reports with a >5% change in LVEF between the initial assessment (by AI or sonographer) and the final assessment by the cardiologist.

Main results


This randomized study showed that initial echocardiogram assessment of LVEF by AI was noninferior and superior to initial sonographer assessment.

-Our reporting is based on the information provided at the ESC Congress-


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