ACC 2020 The SPYRAL HTN-OFF MED Pivotal Trial showed that renal denervation lowers 24h SBP and office SBP compared to sham control in hypertensive patients in absence of medications.
Following the ESC statement, a joint statement of the HFSA, ACC and AHA has now been published on continued use of RAASi during the COVID-19 pandemic.
The ESC Council on Hypertension has released a statement, strongly recommending to continue treatment of ACEi and ARBs in times of the COVID-19 pandemic, as evidence for harmful effects of these drugs in context of COVID-19 is lacking.
A community-based multicomponent intervention led to a greater reduction in BP than usual care among adults with hypertension in rural communities in three South Asian countries.
Sex-specific analysis of BP trajectories using data of >32,000 individuals indicates that BP elevation during life span increased faster in women than in men, starting at 30 years.
A study using data of millions of patients showed that there are no differences in effectiveness between drug classes when initiating monotherapy for hypertension, with the exception of lower risk of MI, HHF and stroke with thiazide or thiazide-like diuretics when compared to ACEi.
A randomized clinical trial of hypertensive patients demonstrates that ingestion of hypertension medication at bedtime reduces asleep ABP and CVD event risk compared to ingestion upon awakening.
CSI Paris Eline Groenland asks Dan Lane about his novel screening method using urine samples that can detect whether hypertensive patients take their drugs. This test may help to improve medical adherence.
ESC 2019 In community-based studies in Colombia and Malaysia, HOPE-4 achieved reduced CV risk, better treatment adherence and healthier behavior with an intervention that targeted previously identified barriers to care.
In the AMBER trial, taking concomitant patiromer enabled more persistent use of spironolactone in patients with resistant hypertension and chronic kidney disease, by reducing the risk of hyperkalemia.
ESC 2019 A stepped-wedge cluster randomized controlled trial showed that a salt-substitution strategy in 6 villages in Peru lowered blood pressure and reduced incidence of hypertension by half.
In a large cohort study of 1.3 million participants, both systolic and diastolic hypertension were associated with composite of MI, ischemic stroke and hemorrhagic stroke, independent of thresholds defining hypertension.